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Diagnose Like a Radiologist : Hybrid Neuro-Probabilistic Reasoning for Attribute-Based Medical Image Diagnosis

During clinical practice, radiologists often use attributes, e.g., morphological and appearance characteristics of a lesion, to aid disease diagnosis. Effectively modeling attributes as well as all relationships involving attributes could boost the generalization ability and verifiability of medical image diagnosis algorithms. In this paper, we introduce a hybrid neuro-probabilistic reasoning algorithm for verifiable attribute-based medical image diagnosis. There are two parallel branches in our hybrid algorithm, a Bayesian network branch performing probabilistic causal relationship reasoning and a graph convolutional network branch performing more generic relational modeling and reasoning using a feature representation. Tight coupling between these two branches is achieved via a cross-network attention mechanism and the fusion of their classification results. We have successfully applied our hybrid reasoning algorithm to two challenging medical image diagnosis tasks. On the LIDC-IDRI benchmark dataset for benign-malignant classification of pulmonary nodules in CT images, our method achieves a new state-of-the-art accuracy of 95.36% and an AUC of 96.54%. Our method also achieves a 3.24% accuracy improvement on an in-house chest X-ray image dataset for tuberculosis diagnosis. Our ablation study indicates that our hybrid algorithm achieves a much better generalization performance than a pure neural network architecture under very limited training data.

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Informasi Detail

Judul Seri

IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE; Vol.44 No.11 Part 1 November 2022

No. Panggil

-

Penerbit

: .,

Deskripsi Fisik

p. 7400-7416

Bahasa

English

ISBN/ISSN

-

Klasifikasi

NONE

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

-

Subjek

BAYESIAN NETWORKS
DEEP NEURAL NETWORKS
MEDICAL IMAGE ANALYSIS
NEURO-PROBABILISTIC REASONING

Info Detail Spesifik

DOI: 10.1109/TPAMI.2021.3130759

Pernyataan Tanggungjawab

Gangming Zhao, Quanlong Feng, Chaoqi Chen, Zhen Zhou, Yizhou Yu

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