High-Dimensional Precision Medicine From Patient-Derived Xenografts

The complexity of human cancer often results in significant heterogeneity in response to treatment. Precision medicine offers the potential to improve patient outcomes by leveraging this heterogene…

Learning Individualized Treatment Rules for Multiple-Domain Latent Outcomes

For many mental disorders, latent mental status from multiple-domain psychological or clinical symptoms may perform as a better characterization of the underlying disorder status than a simple summ…

Introduction to the Theory and Methods Special Issue on Precision Medicine an…

We introduce the Theory and Methods Special Issue on Precision Medicine and Individualized Policy Discovery. The issue consists of four discussion papers, grouped into two pairs, and sixteen regula…

Learning Optimal Personalized Treatment Rules in Consideration of Benefit and…

Analysis of the proportional hazards model with sparse longitudinal covariates

New statistical learning methods for estimating optimal dynamic treatment reg…

Targeted Local Support Vactor Machine for Age-Dependent Classification